Nutrition
A bill introduced Wednesday in the House would create an artificial joints database to root out bad practices and unnecessary surgeries, The New York Times reports. "The bill, co-sponsored by (Democrats) Bill Pascrell Jr. of New Jersey and Lloyd Doggett of Texas, would establish a government-backed registry to track patients" results over time and help detect ineffective surgical practices and faulty devices. Patient registries, in areas like orthopedics, are expected to play an important role in "comparative effectiveness" reviews that the Obama administration hopes will help identify which medical procedures and products work best."
Senate Judiciary Committee Republicans on Wednesday sent a letter to Supreme Court nominee Sonia Sotomayor requesting additional background information to supplement a committee questionnaire, CQ Today reports. The Republicans said that Democrats are rushing the nomination process by scheduling Sotomayor"s confirmation hearing to begin July 13 and that they need more information on the nominee. According to CQ Today, Democrats are unlikely to budge from their determination to confirm Sotomayor before the Aug. 7 recess, although Republicans might convince Leahy to postpone the hearing for a week in exchange for a GOP pledge not to delay a committee vote on Sotomayor for a week, as allowed under the panel"s rules (Perine, CQ Today, 6/10). Among their requests, Republicans asked that Sotomayor provide copies of the Yale Law Journal, for which she served as an editor, and that she elaborate upon her role with the Puerto Rican Legal Defense and Education Fund. White House spokesperson Ben LaBolt said that the Obama administration has made clear that it plans to provide additional information but that it has presented most of the information quickly to allow the Senate to begin its review (Herszenhorn, "The Caucus," New York Times, 6/10). Judiciary Committee ranking member Jeff Sessions (R-Ala.) said that the information requested is not "little itty-bitty matters" but "important" components of Sotomayor"s background. He added, "If we"re going to move forward in a record-breaking time frame, the least we can expect is complete and full answers to these questions." Sen. Orrin Hatch (R-Utah), a senior member on the committee, said there is "a lot of irritation and discomfort" among Republicans "about the way it"s being handled." He added that he does not think Republicans want to filibuster the nomination but implied that they might use procedural tools to slow the process (CQ Today, 6/10).
In a "portrayal that defied logic," George Tiller -- the Kansas abortion provider who was murdered last month -- has been depicted "on Web sites, TV and radio talk shows and in legislative hearings as the reckless "abortionist," willing to euthanize babies close to birth just so the mother could fit into a prom dress or attend a rock concert," Barbara Shelly, a member of the Kansas City Star editorial board, writes in a Star opinion piece. She asks, "Would someone in the third trimester of pregnancy travel to the heart of Kansas and pay a $6,000 fee just to fit into a size six party dress?" Shelly adds that the "overwhelming majority of the 250 to 300 women a year" that sought abortions from Tiller in the second and third trimesters had planned their pregnancies. She profiles a Missouri college professor, pregnant with twins, who traveled to Tiller"s clinic with her husband to obtain an abortion after an amniocentesis revealed that neither fetus would survive and that she faced potentially life-threatening complications if the pregnancy continued. Shelly writes that the woman and others like her went to Tiller "heartbroken and afraid, carrying fetuses with malfunctioning kidneys, missing organs and syndromes certain to cause death in the womb or soon after birth." A smaller number were survivors of rape and incest, including young girls, according to Shelly. The "prom queen who talked her way into a late-term abortion" is a "creation of Tiller"s enemies," Shelly writes, concluding that the "real people" affected by his death are the "thousands who wrote the notes that now serve as a memorial wall to a fallen physician. They are the ones who should define his memory" (Shelly, Kansas City Star, 6/9).
Dr. Mark Horton, director of the California Department of Public Health (CDPH), warned consumers not to eat SENG Chen PiMei Candy, after tests by CDPH found unacceptable levels of lead. Consumers in possession of the candy should discard it immediately.
This week, the Mississippi State Department of Health (MSDH) reported 24 new cases of H1N1 swine flu, bringing the state"s total number of cases to 58. The new cases are in Harrison (7), Jackson (4), Hinds (3), Holmes (2), Rankin (2), Jones (2), Lowndes (2), Lauderdale (1) and Madison (1) counties.
New research published in the June issue of the Journal of the American College of Surgeons reveals that in counties with the highest levels of segregation, an increase in the African-American or Hispanic population was associated with a decrease in the availability and use of surgical services and an increase in the number of emergency room visits. This research supports prior studies that have shown that minority groups in the United States have comparatively poorer access to a range of health care services, often resulting in late diagnosis of illness and delayed treatment.
A team of researchers led by Amy G. Hise, M.D., M.P.H., assistant professor at the Center for Global Health and Diseases, Case Western Reserve University School of Medicine, is the first to discover how the body fights off oral yeast infections caused by the most common human fungal pathogen, Candida.
Nutricia, the European market leader in advanced medical nutrition, has announced the launch of Neocate Nutra, the first and only weaning product made from 100% non-allergenic amino acids. Neocate Nutra has been specifically developed for weaning infants and older children with cows" milk protein allergy (CMPA) and multiple food protein intolerance (MFPI). Unlike many weaning products, Neocate Nutra contains no hidden allergens and is designed to provide children with the key essential nutrients they need for development. With its unique format, Neocate Nutra is suitable for taking infants through the various stages of weaning and also for older children on very restricted diets who are looking for convenient and varied food options.
Vitamin D levels in the body at the start of a low-calorie diet predict weight loss success, a new study found. The results, which suggest a possible role for vitamin D in weight loss, were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
Taking the diabetes medications metformin and rosiglitazone together reverses the adverse effects on bone of rosiglitazone treatment alone in an experimental model, according to a new study done in rats. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C.
Some disease-causing bacteria are becoming resistant to antibiotics because they have peculiar sex lives, say researchers publishing new results in the journal Science. The new study helps scientists understand how bacteria develop resistance to antibiotics, which is a major challenge for those treating infectious diseases, say the authors from Imperial College London.
The National Organization for Rare Disorders (NORD) will honor a senior U.S. Senator, a top Administration official, a cutting-edge television network, and several pioneering companies developing treatments for rare diseases at the 2009 NORD Gala at the National Press Club in Washington, DC, on Thursday, May 14.
New data from Phase 3 European clinical trials reinforce that Wyeth"s (NYSE: WYE) investigational pneumococcal vaccine, Prevenar 13 (Pneumococcal Polysaccharide Conjugate Vaccine, 13-valent [Adsorbed]), has the potential to provide coverage against the 13 most prevalent serotypes associated with pneumococcal disease (PD), the leading cause of vaccine-preventable death in children younger than five worldwide.
In technology that promises to one day allow drug delivery to be tailored to an individual patient and a particular cancer tumor, researchers at the University of California, San Diego School of Medicine, have developed an efficient system for delivering siRNA into primary cells. The work was published on May 17 in the advance on-line edition of Nature Biotechnology.
Statement from Georges C. Benjamin, MD, FACP, FACEP (E), Executive Director, American Public Health Association, "The American Public Health Association applauds the Senate for today passing the Family Smoking Prevention and Tobacco Control Act. The legislation will protect the health of Americans, particularly children, by giving the Food and Drug Administration (FDA) the authority to regulate tobacco products.
The benefits of alcohol are all about moderation. Low to moderate drinking - especially of red wine - appears to reduce all causes of mortality, while too much drinking causes multiple organ damage. A mini-review of recent findings on red wine"s polyphenols, particularly one called resveratrol, will be published in the September issue of Alcoholism: Clinical & Experimental Research; the review is also available at Early View.
Seventeen-year-old Sara Abousuiony, who has been homebound since she was an infant, never imagined that she would be able to leave her home in Cairo, Egypt, and travel to the United States for a life-saving heart procedure.
"Today is an historic day for public health, as the U.S. Senate passed legislation by a bipartisan 79-17 vote that will finally put an end to Big Tobacco"s despicable marketing practices that are designed to addict children to its deadly products. Senate passage of the "Family Smoking Prevention and Tobacco Control Act" (S. 982) has the potential to reduce the scourge of tobacco products, which kill more than 400,000 Americans every year.
Mylan Inc."s (NASDAQ: MYL) Chief Operating Officer Heather Bresch today testified before the U.S. House of Representatives Judiciary Subcommittee on Courts and Competition Policy concerning patent litigation settlements between branded pharmaceutical companies and generic pharmaceutical companies. During her testimony, Bresch conveyed Mylan"s position that the launch of an authorized generic by brand companies during a generic company"s 180-day exclusivity period undermines competition and delays timely access to high quality, affordable generic medications for patients, taxpayers, the government and businesses.
Awarepoint Corporation announced deployment of its Real-time Location System (RTLS) at the Rebecca and John Moores UCSD Cancer Center. This deployment adds a third UCSD Medical Center hospital to Awarepoint"s RTLS coverage, which currently includes the system"s Thornton and Hillcrest campuses. The Awarepoint enterprise RTLS installation has now been expanded to include nearly 1.5 million square feet with more than 2,000 assets under management, covering three hospitals across nearly 14 miles.
Fox Chase Cancer Center researchers have discovered that low-oxygen regions in prostate tumors can be used to predict a rise in prostate-specific antigen (PSA) levels, a marker of tumor recurrence in prostate cancer. The long-term study results were presented at the 2009 American Society of Clinical Oncology annual meeting in Orlando, FL.
Bristol-Myers Squibb Company (NYSE: BMY) announced results of two ORENCIA® (abatacept) studies at the 2009 Annual European Congress of Rheumatology (EULAR) currently being held in Copenhagen, Denmark.
Abraxis Bioscience, Inc. (NASDAQ:ABII), a fully integrated, global biotechnology company, has now made ABRAXANE for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) (nab-paclitaxel) available in China for the treatment of patients with metastatic breast cancer. In a global Phase III clinical trial, and in a Phase II clinical trial in China, the tumor response rate for patients who received ABRAXANE for the treatment of metastatic breast cancer was nearly double the response rate compared to patients who received solvent-based paclitaxel.i
GTx, Inc. (Nasdaq: GTXI) announced results of a Phase II clinical trial evaluating Ostarine™ (MK-2866), an investigational selective androgen receptor modulator (SARM), in patients with cancer induced muscle loss, also known as cancer cachexia. In the study, Ostarine treatment led to statistically significant increase in lean body mass (LBM) and improvement in muscle performance measured by stair climb in patients with cancer cachexia compared to baseline in both the Ostarine 1 mg and 3 mg treatment cohorts. These study results were the subject today of an oral podium presentation at the 2009 Annual Meeting of the Endocrine Society in Washington.
Masimo (Nasdaq: MASI), the inventor of Pulse CO-Oximetry(TM) and Measure-Through Motion and Low-Perfusion pulse oximetry, announced that three new independent studies demonstrating the clinical accuracy and utility of Masimo PVI as a noninvasive and continuous measure of patient fluid status and responsiveness were presented this week at the European Society of Anaesthesiology (ESA) Annual Congress in Milan, Italy.
Dr. Jonathan C. Song, director of the Cornea Institute in the Vision Center at Childrens Hospital Los Angeles and an eye surgeon specializing in corneal diseases and transplantation, has just returned from a medical mission in which he worked with Syrian and Iraqi eye surgeons at the Syrian city of Dier Ezzor. During the medical mission, May 18-22, Dr. Song saw 50 patients and performed eight corneal transplants and five cataract surgeries. In addition to holding training sessions with Syrian ophthalmologists, he also lectured to 25 Syrian and Iraqi medical professionals about advanced eye surgery techniques.
Health Affairs unveiled a series of six studies examining the nursing workforce in the context of health reform. The papers were released at a forum presented by Health Affairs and the Center to Champion Nursing in America (CCNA) that featured a lively discussion among policy-makers, nursing leaders and researchers, and health reform experts. The Center is a joint initiative of AARP, the AARP Foundation and the Robert Wood Johnson Foundation.
Medigap policyholders are overwhelmingly satisfied with their coverage and say it provides good value for their money, according to a new survey released today by the Blue Cross Blue Shield Association (BCBSA) and America"s Health Insurance Plans (AHIP).
In a study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, Saint Louis University"s Center for Vaccine Development is investigating whether the standard vaccine used in foreign countries against tuberculosis offers better protection as a shot, drink or combination of both.
Scientists involved in the National Institutes of Health"s Models of Infectious Disease Agent Study (MIDAS) are developing computational tools to study the emergence, spread and containment of contagious outbreaks, including H1N1.
In these difficult times, when the global health community is facing the dangers of an important new influenza pandemic, a new partnership is forming. The lancet, one of the world÷´s leading medical journals has announced its partnership with the Rockefeller Foundation and the China Medical Board. Together they will develop a major series to evaluate the state of public health in Southeast Asia.
Researchers at the University of Gothenburg, Sweden, have developed a new method to study single cells while exposing them to controlled environmental changes. The unique method, where a set of laser tweezers move the cell around in a microscopic channel system, allows the researchers to study how single cells react to stress induced by a constantly changing environment.
This year the British Transplant Games takes place in Coventry and 900 transplant athletes are preparing to take part. For a handful of these athletes, the Games offers vital training and preparation for other major sporting challenges such as triathlons and marathons. The event organisers, Transplant Sport UK shines the spotlight on these inspiring people, who visibly demonstrate that there is life after transplant, allowing them to train to a high level of fitness against all the odds.
No Additional Risk
Insurers, business owners, and doctors -- three principal interest groups in health reform -- are stepping up their opposition and lobbying efforts as details of the health plans emerge.
CombinatoRx, Incorporated (NASDAQ: CRXX) announced the presentation of full data on Synavive (CRx-102) Phase 2 knee osteoarthritis (OA) trial (COMET-1) at EULAR 2009, the Annual European Congress of Rheumatology in Copenhagen on June 12, 2009. The presentation, "CRx-102, a dissociated glucocorticoid (GC), and prednisolone provide safe and effective pain relief in knee osteoarthritis (OA) in a placebo-controlled Phase 2 trial (COMET-1)", Huttner et.al., describes the full, modified intent-to-treat, safety and efficacy results of Synavive in this clinical trial:
Data presented at the 19th Scientific Meeting of the European Society of Hypertension (ESH) confirm that Diovan® (valsartan) and valsartan-based combinations deliver sustained, 24-hr blood pressure (BP)-lowering efficacy2-6.
The NFU has told a European Commission review of anti-dumping duties imposed on fertiliser from the Ukraine that such measures act as artificial trade barriers and, given the importance of fertiliser to agriculture, can curb profitability of farms across the UK and EU.
Cellulose is a fibrous molecule that makes up plant cell walls, gives plants shape and form and is a target of renewable, plant-based biofuels research. But how it forms, and thus how it can be modified to design energy-rich crops, is not well understood. Now a study led by researchers at the Carnegie Institution"s Department of Plant Biology has discovered that the underlying protein network that provides the scaffolding for cell-wall structure is also the traffic cop for delivering the critical growth-promoting molecules where needed. The research, conducted in collaboration with colleagues at Wageningen University in the Netherlands and published in the advance online publication (AOP) of Nature Cell Biology on June 14th, is a significant step for understanding how the enzymes that make cellulose and determine plant cell shape arrive at the appropriate location in the cell to do their job.
Could sleep be a critical component to maintaining a healthy body weight? According to new research presented on Sunday, May 17, at the American Thoracic Society"s 105th International Conference in San Diego, body mass index (BMI) is linked to length and quality of sleep in a surprisingly consistent fashion.
New research by scientists at The Scripps Research Institute and other institutions provides a close-up look at the cone-shaped shell that is the hallmark of human immunodeficiency virus (HIV), revealing how it is held together - and possible ways to break it apart.
The Rural Doctors Association of Australia (RDAA) says the establishment of the new Indigenous Health, Rural and Regional Health and Regional Services Delivery portfolio and the appointment of Warren Snowdon MP as the new Minister is recognition of the significant problems that Australians who live in the bush have in accessing health care services.
Healthcare professionals can now order a number of Macmillan Cancer Support"s free, high-quality cancer information booklets in CD format.
When a patient"s first symptoms of rheumatoid arthritis (RA) occur in winter, the severity of their RA (as measured by the modified Total Sharp Score, mTSS, an assessment of erosion and joint space narrowing) was rated more severe at six months, when compared to patients whose RA first became symptomatic in summer (Odds Ratio (OR) =2.82 [1.14;7], p=0.0255). Furthermore, RA patients with their first symptoms in spring showed poorer radiographic outcome compared to summer-onset patients (OR=2.83 [1.10;7.37], p=0.0322), according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark.
A protein known to play a role in growth of some types of leukemia appears to have a mixed function in breast cancer development, say researchers from the Lombardi Comprehensive Cancer Center at Georgetown University Medical Center (GUMC).
In June, the Royal College of Physicians will be holding a series of workshops with local schools and families exploring The Great Plague of 1665 and the involvement of the Royal College of Physicians.
Vitamin D deficiency was found to be prevalent in cancer patients regardless of nutritional status, according to the results of a recent study conducted at Cancer Treatment Centers of America (CTCA). Based on these results, CTCA researchers determined that screening for vitamin D deficiency and aggressive vitamin D repletion should be considered for all people with cancer.
Proteolix, Inc. announced that in an article published in Nature Medicine, Proteolix"s selective immunoproteasome inhibitor PR-957 was shown to block disease progression in mouse models of rheumatoid arthritis in a dose-dependent manner and to completely eliminate visible signs of disease at the highest dose. The anti-inflammatory effect induced by PR-957 was rapid and long-lasting, lowering expression of multiple inflammatory mediators, including TNF-a and IL-6. Disease regression was evident 24 hours after dosing and a complete amelioration of disease was achieved with a single dose. When compared to anti-TNF-a therapy (etanercept), PR-957 mediated a more rapid resolution of clinical symptoms, including joint inflammation, and was more effective than etanercept in a model of aggressive arthritis.
Amira Pharmaceuticals, Inc. announced that it will present preclinical data from its LPA1 receptor antagonist program on June 30, 2009 at the Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference in Carefree, Arizona.
If hip resurfacing is an option, the surgeon will simply reshape the damaged surface of the femoral ball and then cover it with a round metal cap. The limitation here is that the procedure only works for bone that is not too damaged by arthritis. Generally speaking, surface replacements are not performed on patients with serious arthritic conditions, because if the bone is not strong enough, there is a small but real risk of fracturing. Therefore the average age of resurfacing patients may be 50 years or younger. Statistically, the resurfacing operation is an option for about 7 out of a 100 patients.
Medical Protection Society (MPS) GP members, who are expected to work outside of their normal duties during a pandemic flu, should feel confident that they can turn to the MPS for assistance, in the event they are subject to a clinical negligence claim or other medicolegal matter such as a complaint.
The results of a new survey of 400 UK healthcare professionals, conducted by TNS Healthcare UK and sponsored by Merck Sharp & Dohme Limited and Schering-Plough Limited, reveal that the majority of GPs surveyed (82% of the 100 GPs) believe that the cholesterol indicator (CHD 08) should remain a priority area in the Quality and Outcomes Framework (QOF).1 They also believe that it would be useful for the QOF to reflect National Institute for Health and Clinical Excellence (NICE) guidelines, with 67% of GPs supporting specific lower lipid targets for type 2 diabetes and 65% for secondary prevention.1
US researchers found that people with memory problems who are depressed are at higher risk of developing Alzheimer"s disease than people who
Galapagos NV (Euronext: GLPG) announced that it has initiated Phase I clinical development of its integrin receptor antagonist (IRA), GLPG0187. This is the second small molecule therapeutic from Galapagos" internal drug discovery program to enter the clinic in 2009. Candidate drug GLPG0187 could offer a promising new therapeutic approach for treating cancer patients. Initial development will focus on bone metastases from prostate and breast cancer.
"With Republicans fighting the idea of a government-run health insurance plan, members of President Barack Obama"s team said Sunday that they are open to a compromise: a cooperative program that would expand coverage with taxpayer money but without direct governmental control," the Associated Press reports. The non-profit, health insurance cooperatives were suggested in Congress by Sen. Kent Conrad, D-N.D., and HHS Secretary Kathleen Sebelius said the concession could be a path to bipartisan health reform legislation (Elliott, 6/15).
Celebrity Elisabeth Hasselbeck is generating a lot of buzz about Gluten-Free living, but International Celiac Expert Shelley Case, RD warns consumers why going gluten-free before being screened for celiac disease can be hazardous to your health!
Reuters reports that "a North American shortage of medical isotopes has forced many U.S. hospitals to begin rationing scores of diagnostic tests, and doctors said on Friday they see no quick solution." The shortage is due to last month"s shut down of a "nuclear reactor in eastern Ontario that produces a third of the world"s supply of medical isotopes, used in scans to check for an impending heart attack or see if cancer has spread." Reuters notes that "the Canadian plant is one of five aging reactors worldwide -- none located in the United States -- to produce molybdenum-99, the most commonly used medical isotope. The rapidly decaying substance has a shelf life of just 67 hours, making it impossible to stockpile."
Wrong Way On Health Reform Washington Post
Today, the Israeli medtech startup company CLT Ltd. announced the establishment of Closed Loop Therapies (CLT) BV - a joint venture between Erasmus University Medical Centre (Rotterdam, the Netherlands), a highly prominent medical institute in Europe, and CLT Israel. The joint venture aims to develop and commercialise a novel therapeutic system, consisting of an arrhythmia-detecting drug pump combined with a unique drug, for automatic and immediate treatment of emerging atrial fibrillation (AF). Market size is estimated at 2.5-3 billion Euro, annually.
Cameron Health, Inc. announces CE approval for Cameron Health"s Subcutaneous Implantable Defibrillator (S-ICD®) System. The minimally invasive S-ICD System is prescribed for use in patients at risk of Sudden Cardiac Arrest (SCA). The system is unique in that the implantation of the system is entirely subcutaneous; no leads are in or on the heart. Additionally, there is no imaging equipment required for placement of the S-ICD System, as all of the components may be positioned using anatomical landmarks.
The Government has, for the first time, declared its support for what could be England"s first Autism Bill. The National Autistic Society (NAS) celebrated the move as a vital development for people with autism as Care Services Minister Phil Hope committed to enshrining in law a raft of new measures, via the Autism Bill, which could drive a dramatic improvement in local authority and NHS services for people with the condition.
A study in the June 15 issue of the Journal of Clinical Sleep Medicine shows that the complaints of fatigue and tiredness in patients with obstructive sleep apnea (OSA) improved significantly with good adherence to continuous positive airway pressure (CPAP) therapy, suggesting that - like the symptom of excessive daytime sleepiness - these complaints are important symptoms of OSA.
Research by a Hebrew University of Jerusalem professor has led to the development of a product that has been shown in clinical trials to be successful in halting the growth of various types of cancer cells.
Scientists from A*STAR"s Singapore Immunology Network (SIgN) and the University of Milano-Bicocca, Italy, have discovered another signaling pathway for the activation and apoptosis, or programmed cell death, of dendritic cells[1] . This discovery was published in the advanced online publication of Nature on 15 Jun 2009.
Scarring of the liver, which can progress to cirrhosis and/or cancer of the liver, is caused by persistent liver damage, such as occurs in those with untreated hepatitis C or alcoholism. Although such scarring (fibrosis) develops in an inflammatory environment, the role of inflammatory molecules has not been well defined. However, a team of researchers at Columbia University, New York, and UCSD, La Jolla, has established that the proteins CCR1 and CCR5 and the soluble inflammatory molecules that bind to them promote the development of liver fibrosis in mice.
Calcium Supplementation Has No Weight-loss Benefit for Obese Patients
Recently, researchers at the European Molecular Biology Laboratory"s European Bioinformatics Institute (EMBL-EBI) launched a new database, the Gene Expression Atlas, which allows scientists to search and compare gene expression data at unprecedented detail and scope. Observing how gene expression varies in different cell types, tissues and under disease conditions can help researchers understand gene function and to develop new drugs and therapies.
Loss of feeling in the feet is a common complication of diabetes, so it"s critical that those with the disease wear shoes that fit properly and check their feet often for cuts or sores. Left untreated, a diabetic"s foot wound can lead to a serious infection or even require amputation.
Studying how the mouth wards off diseases will have implications for understanding overall how people stay healthy. The Case Western Reserve University School of Dental Medicine will use a five-year, $9.5 million grant from the National Institutes of Health"s National Institute for Dental and Craniofacial Research - the largest grant ever in the dental school"s 117-year history - to study oral health as one of the human body"s frontline defenses against infections.
Has the key to reducing breast cancer gotten lost in the race for a cure? A new book, No Family History, presents compelling evidence that exposure to everyday products such as cosmetics and toiletries, hormones in food, household cleaners and pesticides is behind the dramatic increase in breast cancer and argues that the solution is simple: prevention.
A new technique known as stereotactic body radiotherapy (SBRT) is safe for patients with recurrent head and neck cancers and may improve their quality of life, according to researchers from the University of Pittsburgh Cancer Institute (UPCI). Results of the phase I study were reported today in the International Journal of Radiation Oncology, Biology, Physics.
June is National Osteoporosis Month and health experts from NHS Somerset are urging people to look after their bones by living well and eating well.
New data presented showed that pitavastatin is an effective treatment for the management of dyslipidemia in elderly patients, with a similar safety and tolerability profile to low-dose pravastatin. The Phase III data were presented by Kowa, at the XV International Symposium on Atherosclerosis in Boston.
New data announced at Heart Rhythm 2009, the annual congress of the Heart Rhythm Society, demonstrate that patients implanted with the investigational EnRhythm MRI™ SureScan™ pacing system experienced no complications related to the use of magnetic resonance imaging (MRI). Sponsored by Medtronic, Inc. (NYSE: MDT), the study confirms that the pacing system can help cardiac device patients benefit from the use of MRI, a critical imaging technique commonly used in disease diagnosis. Currently, due to safety considerations, there are no implantable pacemakers or defibrillators approved for use with MRI in the United States. Commercially released in Europe last fall, the EnRhythm MRI SureScan system is the world"s first and only pacing system designed and approved for use with MRI.
NECT (Nifurtimox-Eflornithine Combination Therapy), a new treatment option for sleeping sickness, a fatal disease that threatens 60 million people across sub-Saharan Africa, has been added to the Essential Medicines List (EML) of the World Health Organization (WHO). The inclusion is based on an application submitted by the non-profit Drugs for Neglected Diseases initiative (DNDi), supported by the international medical humanitarian organization Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF), and Epicentre, MSF"s epidemiological research center.
Hologic, Inc. (Hologic or the Company) (Nasdaq: HOLX), a leading developer, manufacturer and supplier of premium diagnostics, medical imaging systems and surgical products dedicated to serving the healthcare needs of women, announced that it has received Food and Drug Administration (FDA) clearance for its R2(TM) DigitalNow(TM) HD software application.
It is well known that chronic pain and clinical depression go together, but a study in The Journal of Pain, published by the American Pain Society, shows that the connection between pain and depression is strongest in middle-age women and African Americans.
Marking a unique milestone in prostate cancer surgery, the director of urologic oncology at The Cancer Institute of New Jersey (CINJ) has completed his 500th robotic prostatectomy at Robert Wood Johnson University Hospital (RWJUH), the Flagship Hospital of CINJ, which is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.
The Congressional Budget Office has found that the Senate Health, Education, Labor and Pensions Committee"s health reform proposal would cost taxpayers about $1 trillion over the next decade and only insure 16 million people, about one-third of uninsured Americans, Politico reports. More individuals would lose employer-provided insurance they already have, or move away from government programs, prompting Republicans to say in a memo, "For all of the money the bill spends, the coverage increase is relatively anemic."
The battle over health care reform will happen in the Senate, even though President Obama keeps getting all the attention, The Washington Post"s The Fix reports.
A fee for patients at Cleveland Clinic is upsetting some patients who are complaining to the Ohio hospital, their insurance companies and even members of Congress. They say they can"t afford the expense in the current economy, according to The Plain Dealer.
The Associated Press reports that the VA "opened the doors of its health care system Monday to about 266,000 nondisabled veterans with moderate incomes, some of whom have been shut out of those benefits. The veterans eligible are from a category known as "Priority 8." They have no illnesses or injuries attributed to their military service, and they earn more than the average wage in their communities." The AP notes that such veterans were previously denied enrollment because of a cost-savings move in 2003, but the VA is expanding eligibility by raising income restrictions from about $29,000 to $32,000, which is adjusted for the cost of living. The effort represents part of President Barack Obama"s campaign promise to bring all veterans into the VA"s system. The AP notes that: "In 1996, Congress ordered the agency to open health care to nearly all veterans, but lawmakers also gave the VA secretary the authority to suspend enrollments" (Hefling, 6/15).
You Be Obama New York Times
Taking popular cholesterol-lowering statin drugs, such as Lipitor® (atorvastatin), does not lower the risk of pneumonia. That"s the new finding from a study of more than 3,000 Group Health patients published online on June 16 in advance of the British Medical Journal"s June 20 print issue.
Children born without thymus glands have given Duke University Medical Center researchers a rare opportunity to watch as a new immune system develops its population of infection-fighting T-cells.
A new study by Indiana University-Purdue University Indianapolis (IUPUI) researchers contradicts the conventional wisdom that living near a fast food outlet increases weight in children and that living near supermarkets, which sell fresh fruit and vegetables as well as so called junk food, lowers weight.
The kids are playing in the backyard and enjoying their break from school. Your husband is enjoying the day on the golf course. And you"re cleaning up the house, folding laundry and cooking three meals. Sound familiar?
A new study by The George Institute for International Health has found Tai Chi to have positive health benefits for musculoskeletal pain. The results of the first comprehensive analysis of Tai Chi suggest that it produces positive effects for improving pain and disability among arthritis sufferers.
Gene regulatory networks in cell nuclei are similar to cloud computing networks, such as Google or Yahoo!, researchers report today in the online journal Molecular Systems Biology. The similarity is that each system keeps working despite the failure of individual components, whether they are master genes or computer processors.
A new study by UK scientists showed that cooking carrots whole preserves their anti-cancer properties better than cooking them sliced or
The ESMO Conference: 11th World Congress on Gastrointestinal Cancer opens next week in Barcelona, Spain with a substantial increase in registered attendees over previous years, providing important practice updates and promising new research into the numerous types of cancers that affect the gastrointestinal tract. "Ongoing study and changing standards in the treatment of gastrointestinal cancers have made it mandatory for clinicians to continually update their knowledge to keep up with advances in the field," says Congress co-chair Dr. Eric Van Cutsem. "The World Congress on Gastrointestinal Cancer addresses the immediate practice implications of these changes."
A leading Danish cancer hospital has treated its first patient using RapidArc(R) radiotherapy after installing eight advanced radiotherapy treatment machines from Varian Medical Systems (NYSE: VAR) of Palo Alto, California. Herlev Hospital, to the north-west of Copenhagen, delivered the fast and efficient RapidArc treatment to a prostate cancer patient using a Clinac(R) iX linear accelerator.
How molecules of the oldest branch of the human immune system have interconnected has remained a mystery. Now, two new structures, both involving a central component of an enzyme important to the complement system of the immune response, reveal how this system fights invading microbes while avoiding problems of the body attacking itself.
A German study published in the current issue of Psychotherapy and Psychosomatics addresses the differences between inpatient versus day clinic treatment of bulimia nervosa.
After nine years of providing health care for the population in Bakool region, Doctors Without Borders/Mç©decins Sans Frontiç¨res (MSF) has reached the regrettable conclusion that it does not have sufficient security to continue its work. This decision was MSF"s alone and the organization was not expelled by the authorities. MSF medical activities elsewhere in Somalia continue.
Food, fitness or familyò€¦which one is most to blame for childhood obesity? New research from Mintel shows today"s parents aren"t sure, and they"re feeling overwhelmed and worried as they try to prevent obesity in their own children.
Diabetes UK will attend the prestigious Innovation Expo at London"s ExCeL on 18 to 19 June.
"Democrats Tom Daschle and George Mitchell are set to join Republicans Bob Dole and Howard Baker on Wednesday to release a $1.2 trillion proposal that would be fully paid for with a combination of spending cuts and tax increases," the Associated Press reports. The proposal from the four former Senate leaders "combines ideas from both political parties to guarantee coverage for all" and is an attempt to "prevent a repeat of the 1990s standoff over health care."
The French government has awarded Baylor Health Care System with an $8 million grant to develop a therapeutic method of controlling HIV without medication, the Dallas Morning News reports. The funds will go toward establishing an HIV research unit at Baylor"s Institute of Immunology Research, which will focus on researching the immune system cells of people living with HIV (Roberson, Dallas Morning News, 6/17).
NAEA calls upon Congress to reject the President"s request to eliminate abstinence education funding from the 2010 budget. NAEA also urges the Administration to retract its overreaching decision to zero out abstinence education funding. Abstinence education programs must continue using the same legislative guidelines as have been applied under the previous administrations of Clinton and Bush.
A new approach to stimulating immune cells enhances their anticancer activity, resulting in a powerful anti-tumor response in mice, according to a study by researchers at the National Cancer Institute, a part of the National Institutes of Health. This work represents an important advance in the development of immunotherapy for cancer and appears online June 14, 2009 in Nature Medicine.
Advocates on both sides of the abortion-rights debate are anticipating the White House"s release of its "common ground" reproductive health proposals, including policies aimed at preventing unintended pregnancies and reducing the need for abortion, U.S. News & World Report reports. President Obama in February tasked the White House Office of Faith-Based and Neighborhood Partnerships with determining how to "support women and children, address teenage pregnancy and reduce the need for abortion." Along with the new White House Council on Women and Girls, the office since April has been conducting meetings with advocates on both sides of the abortion-rights debate to develop policy proposals. U.S. News reports that according to some involved in the process, the results could be announced as early as this summer. According to U.S. News, whether the White House can attract more support from conservative groups without alienating abortion-rights advocates at its base represents the "biggest test yet" of Obama"s "vow to be a peacemaker in the nation"s culture wars."The White House solicited recommendations from groups in four areas: reducing unintended pregnancies, increasing access to adoption, supporting maternal health and reducing the need for abortion. The administration has stressed that it wants to avoid influencing women"s decisions on abortion but that there needs to be support for individuals who decide to carry pregnancies to term. To date, the White House has given little indication on what the final plan will look like, and the wait for the proposals" release has left advocates on both sides of the debate "jittery" over whether their interests will be represented, according to U.S. News.Kristen Day, head of Democrats for Life, said that "[t]here were definitely areas of disagreement" during the meetings but that "for the most part, people were respectful and were doing more listening than debating." Nancy Ratzan -- president of the National Council of Jewish Women and an abortion-rights supporter -- said, "I have real concerns about understanding those issues from a faith perspective as opposed to a scientific and individual rights perspective." She added, "You"re creating the possibility that the religious views of some are going to be imposed on others." Richard Land, head of public policy for the Southern Baptist Convention, which opposes abortion rights, said, "I"m in a trust but verify mode." Land added that he has "seen some signs that they are eagerly seeking common ground and other signs that they"re not."According to U.S. News, some antiabortion-rights groups have said that too much emphasis on preventing unintended pregnancies through strategies like comprehensive sex education and increased access to contraception could cause them to oppose the White House"s plan, even if they agree with certain aspects. Instead, these groups would like Obama to support the Pregnant Women Support Act, which aims to discourage abortion through assistance to economically distressed pregnant women. The Planned Parenthood Federation of America opposes the bill, which it says would "attempt to influence, rather than inform, a woman"s decision whether or not to have an abortion."Laurie Rubiner, vice president for public policy at Planned Parenthood, said that the Obama administration is "strongly pro-choice" and that she is "hopeful their policy will be helpful on reducing unintended pregnancies." Large religious groups that typically oppose abortion rights -- like the Southern Baptist Convention and the U.S. Conference of Catholic Bishops -- also say they are hopeful that the White House"s plan will satisfy groups on both sides. Nancy Wisdo, associate general secretary for USCCB, said the group is "willing to work with anyone who tries to reduce the number of abortions and help women who choose to bring their babies to term." She added that USCCB is "taking the White House at its word that this is going to be a serious effort" (Gilgoff, U.S. News & World Report, 6/16).
Injuries to mothers during childbirth decreased significantly between 2000 and 2006, according to the latest news and numbers from the Agency for Healthcare Research and Quality. The number of mothers who experienced injuries while giving birth vaginally without the use of forceps or other instruments dropped by 30 percent. For mothers giving birth vaginally with the use of instruments and by cesarean section, injuries declined about 20 percent.
A Minnesota program that provides psychiatric medications to low-income patients received a 2009 Community Leadership Award honorable mention from America"s Health Insurance Plans. The awards, which were announced at AHIP"s annual Institute in San Diego, recognize programs that address a community need.
Cytokinetics, Incorporated (NASDAQ: CYTK) announced that the company has initiated a first-time-in-humans, Phase I clinical trial of CK-2017357 in healthy male volunteers. CK-2017357 is a fast skeletal muscle troponin activator and is the lead drug candidate that has emerged from the company"s skeletal sarcomere activator program. CK-2017357 selectively activates the troponin complex and increases its sensitivity to calcium, subsequently leading to an increase in skeletal muscle force. This mechanism of action has demonstrated encouraging pharmacological activity in preclinical models that may relate to the potential treatment of diseases associated with aging, muscle wasting, and neuromuscular dysfunction.
Arrayit Corporation (OTCBB: ARYC), a leading manufacturer of products and services for disease prevention, treatment and cure, announced that its microarray-based diagnostic test, patented under the trade name Variation Identification Platform (VIP), is ready for manufacture and distribution. A breakthrough screening test using VIP will allow clinicians and researchers to test and detect the H1N1 swine flu virus in population wide studies.
An important breakthrough in fungal toxin biology has been made possible through the use of Biolog"s Phenotype MicroArray technology. This major advance is described in two recent publications from a group at CSIRO in Queensland, Australia. The work by Donald Gardiner and his collaborators has recently been published in online editions of the journals Fungal Genetics and Biology and Microbiology.
A comprehensive survey of veterinary students concludes that one in three find themselves in difficult or severe financial situations, more than half have suffered from stress, over a fifth from depression, over a quarter from anxiety and one in every 14 from an eating disorder.