Mental Health
Biophysicists long for an ideal material - something more structured and less sticky than a standard glass surface - to anchor and position individual biomolecules. Gold is an alluring possibility, with its simple chemistry and the ease with which it can be patterned. Unfortunately, gold also tends to be sticky and can be melted by lasers. Now, biophysicists at JILA have made gold more precious than ever - at least as a research tool - by creating nonstick gold surfaces and laser-safe gold nanoposts, a potential boon to laser trapping of biomolecules.
UBC researchers have created the world"s first animal laboratory experiment to successfully model human gambling. The advance will help scientists develop and test new treatments for gambling addictions, a devastating condition that affects millions worldwide.
Living in an area with more fast food outlets and convenience stores than supermarkets and grocers has been associated with obesity in a Canadian study. Researchers writing in the open access journal BMC Public Health have shown that your local food environment can affect your weight.
A $4.15 million, four-year National Institutes of Health grant will enable researchers at the Indiana University School of Medicine to conduct the first health study of teenage boys using cellular telephones.
Sanofi-aventis, a French global healthcare company that makes vaccines announced on Wednesday that it will be giving the World Health
Mental health refers to our cognitive, and/or emotional wellbeing - it is all about how we think, feel and behave. Mental health, if somebody has it, can also mean an absence of a mental disorder. Approximately 25% of people in the UK have a mental health problem during their lives. The USA is said to have the highest incidence of people diagnosed with mental health problems in the developed world. Your mental health can affect your daily life, relationships and even your physical health. Mental health also includes a person"s ability to enjoy life - to attain a balance between life activities and efforts to achieve psychological resilience.
A radically different approach to choosing the best treatment options for early breast cancer has been proposed by an international panel of experts in a report from the 11th St Gallen conference.
Gastroenteritis means irritation and inflammation of the gastrointestinal tract, which includes the stomach and small and large intestines. The condition is usually due to bacteria, food poisoning, parasites, or viruses, and it often results in diarrhea, abdominal pain, nausea, and vomiting. Gastroenteritis is commonly called gastric flu or stomach flu although it has no relation to the influenza virus.
A new landmark collaboration between the Global Alliance for TB Drug Development (TB Alliance), a not-for-profit, product development partnership, and Tibotec Inc., (Tibotec), a global pharmaceutical company, has been announced at the Pacific Health Summit in response to the urgent need to accelerate the discovery and development of new drugs to fight tuberculosis (TB).
The American Society of Interventional Pain Physicians (ASIPP) announced that the National All Schedules Prescription Electronic Reporting (NASPER) Act has received the support of Senator John D. Rockefeller IV of West Virginia and Senator Bob Corker of Tennessee.
Osmetech (LSE:OMH) announced that it has submitted a request to the US FDA for Emergency Use Authorization (EUA) for its Respiratory Pathogen Test Panel test to be used to screen for the swine flu virus.
Health officials said on Thursday that it looks like the novel H1N1 swine flu virus will continue to spread in the US through the summer months,
The World Health Organization and UNICEF today called on governments to strengthen risk reduction measures in four key areas so that health and education systems are able to cope with disasters, including the risks from climate change. These are:
The Honourable Leona Aglukkaq, Minister of Health, and Dr. Chen Zhu, Minister of Health for the People"s Republic of China, today signed a Plan of Action for continued cooperation between the two countries on health priorities of mutual concern. The signing ceremony followed discussions among senior Canadian and Chinese health officials and experts on a range of health issues, including strengthening and reform of health-care systems, primary health care and food safety.
A new sensor device allowing doctors to receive data on the precise amount of radiation being delivered to tumors and surrounding tissue is now being offered at Maury regional Medical Cancer Center. Maury Regional Medical Center is the first in Tennessee to use the technology called DVS® (Dose Verification System) for breast cancer patients undergoing radiation treatment.
The AMA welcomed a proposed increase in tobacco tax. The AMA has always supported increased tax and price signals on products that are bad for your health in order to reduce consumption. This is an opportunity to make health gains for individuals, and the revenue could support essential health care for the increasing unemployed.
The House State-Foreign Operations Appropriations Subcommittee "unanimously approved its FY10 funding measure without any amendments" on Wednesday, "deferring expected fights for the full committee markup in a week," CongressDaily reports.
"Decibels for Life", the new campaign from Siemens Hearing Instruments, has been launched to maintain awareness of hearing loss. It will also champion hearing innovations that help overcome impairments leading to an improved quality of life.
American Public Media"s "Marketplace" on Tuesday examined how some women and their partners are deciding to have more children, a choice that runs contrary to birth rate trends during past economic recessions. Stephanie Ventura, a demographer at the National Center for Health Statistics, said that in previous severe economic recessions, birth rates have decreased or stabilized. It is too soon to tell whether the current recession will affect birth rates because the most recent birth data are from July 2008. Ventura also noted that the data will encompass a broad range of personal choices, including people who delayed pregnancy and those who went forward with plans to have children despite the recession.According to "Marketplace," some women who have lost jobs but have other s of income believe that having time away from work is a good opportunity to plan a pregnancy. Ellen Galinsky, president of the Families and Work Institute, called this rationale "very clever" but added that being out of work only "gives you a break as long as you"ve got health insurance coverage, or unemployment, or some other of income that you can depend on." Galinsky said, "This country is increasingly becoming family centric. There is much more of an emphasis on children and families and being with them and taking good care of them than there has been before" (Keith, "Marketplace," American Public Media, 6/16).
A recent study from Columbia University"s Mailman School of Public Health shows that since 2003, there has been a 10% decrease in contraception use among teenagers, while their level of sexual activity has not changed, a New York Times editorial states. From 1991 to 2003, increased use of contraceptives among teens was a significant factor in declining rates of teenage pregnancy, the editorial says. According to the study"s authors, the decrease in contraception use since 2003 is consistent with recent increases in teen birth rates. According to the editorial, the study"s authors suggest a "link between the shift in use of contraception and one of former President George W. Bush"s great social-policy follies: highly restrictive abstinence-only sex education programs that deny young people information about sexually transmitted diseases, contraceptives and pregnancy." The editorial adds, "To the extent that these programs even mention condoms, typically it is to disparage their effectiveness." In response to "mounting evidence of the program"s danger as a public health strategy," many states have forgone federal abstinence-only funds, the editorial says. As part of his budget proposal, President Obama has called for redirecting some abstinence-only funds and additional money to a new teen pregnancy prevention initiative that stresses comprehensive sex education. The editorial concludes that this "science-based effort to protect the health of young people" and reduce the number of unintended pregnancies "should win support from lawmakers on both sides of the aisle -- and both sides of the abortion divide" (New York Times, 6/18).
Pomegranate juice may be beneficial in men who have undergone standard treatment for localized prostate cancer, according to a long-term study presented at the 104th Annual Scientific Meeting of the American Urological Association.
Folic acid, or vitamin B9, may help treat allergic reactions and allergy symptoms, according to researchers from the Johns Hopkins Children"s Center.
Most healthy 25 year olds don"t stay up at night worrying whether they are going to develop diabetes in middle age. The disease is not on their radar, and middle age is a lifetime away.
New evidence underscores the theory of human origin that suggests humans most likely share a common ancestor with orangutans, according to research from the University of Pittsburgh and the Buffalo Museum of Science. Reporting in the June 18 edition of the Journal of Biogeography, the researchers reject as "problematic" the popular suggestion, based on DNA analysis, that humans are most closely related to chimpanzees, which they maintain is not supported by fossil evidence.
Individuals interested in cancer research and disease management are invited to attend the 26th International Conference entitled, "Advances in the Applications of Monoclonal Antibodies in Clinical Oncology and Symposium on Cancer Stem Cells."
Studies performed in three animal models confirmed the safety and intensive immunogenicity of a new type of intranasal H5N1 influenza vaccine, according to the latest preclinical study data announced today by the Vienna based firm, Avir Green Hills Biotechnology. The study data was just published in PloS One, the Public Library of Science.
The Multiple Myeloma Research Consortium (MMRC), an innovative research model comprised of a network of 15 academic Member Institutions across North America and leadership in Norwalk, Connecticut, announced preliminary data from an analysis showing that clinical trials opened through its clinical trials network were activated 30 to 40 percent faster than comparable clinical trials in oncology. Based on the implementation of specific business solutions, particularly scientific leadership, standardized clinical contracts and on-site project management res, the MMRC has been able to decrease by an average of 100 days the time from the development and finalization of the trial"s protocol to actual patient enrollment.
GP groups and Aboriginal community controlled health services from around
New plans to improve the support and care for individuals and their families living with dementia were announced by Health Minister Edwina Hart.
Women are under too much pressure to lose weight quickly after giving birth, according to German Institute
WHAT
Statement from Texas Medical Association President William H. Fleming III, MD, in response to today"s veto of House Bill 3485 by Gov. Rick Perry.
Superior intelligence is no defense against the effects of attention deficit and hyperactivity disorder, Yale researchers have found.
AIDS Re Center of Wisconsin Chief Operating Officer Mike Gifford said that Wisconsin has the lowest AIDS death rate in the nation, WPR News reports. Gifford said that CDC data indicate that Wisconsin and Minnesota have one AIDS death annually for every 100,000 people. He credits a strong system of health care professionals and state and private support for the low death rate, but noted that hundreds of people living with HIV in Wisconsin are not getting the services they need (Simonson, WPR News, 6/18).
Senate Passes Bill Including Flu Funds
Neurocrine Biosciences, Inc. (Nasdaq: NBIX) announced additional positive safety and efficacy results from its Phase IIb clinical trial known as the Petal Study (603 study) using its proprietary, orally-active non-peptide Gonadotropin-Releasing Hormone (GnRH) receptor antagonist, elagolix, in patients with endometriosis. The Petal Study enrolled 252 patients, with a confirmed diagnosis of endometriosis, into three treatment groups; elagolix 150 mg once daily, elagolix 75 mg twice daily, or depo-subQ provera 104(TM) (DMPA) for six months of treatment followed by six months of no treatment. Database lock and unblinding of the full 48 week data set has provided more insight on the clinical benefits and safety profile of elagolix for the treatment of pain associated with endometriosis.
The U.S. Environmental Protection Agency (EPA) plans to switch to a new generation of animal-free tests for predicting the toxicity of chemicals to humans, according to an article scheduled for the June 22 issue of Chemical & Engineering News, ACS" weekly newsmagazine.
Rearrangements of all sizes in genomes, genes and exons can result from a glitch in DNA copying that occurs when the process stalls at a critical point and then shifts to a different genetic template, duplicating and even triplicating genes or just shuffling or deleting part of the code within them, said researchers from Baylor College of Medicine in a recent report in the journal Nature Genetics. The report further elucidated the effect of the fork stalling and template switching mechanism involved in some forms of copy number variation.
"Moving to a more continuous follow-up approach would have the tremendous advantages of enhancing patient safety, decreasing physician and nurse work load, and allowing health staff to focus on medical emergencies," urged Professor Angelo Auricchio, from the European Heart Rhythm Association (EHRA) and official spokesperson of the European Society of Cardiology (ESC), adding that such systems may have the additional advantage of being more cost effective for health care providers.
Patients with an Implantable Cardioverter Defibrillator (ICD) have an ongoing risk of sudden incapacitation that might cause harm to others while driving a car. Driving restrictions are imposed making these recommendations an important guideline for patients.
The fulfilment which so many people increasingly derive from competitive sports and endurance training comes with a real - even if rare - twist. Because, while most people will enjoy the benefits and pleasures of exercise, there are a few for whom regular athletic training will increase the risk of cardiac arrhythmias and even sudden death, especially among those in middle-age or with pre-existing cardiac diseases.
There are few things as vital to health and well-being as a good night"s sleep. Yet millions of us -- nearly 50 million according to the National Sleep Foundation -- suffer from chronic sleep problems or disorders. Every year, more and more scientific studies are showing correlations between poor or insufficient sleep and disease. Now there is a simple, easy way to quantify and measure sleep problems with patient populations.
One in five people fall below the official poverty line following the death of their partner. "Hence the recent fall in the value of annuities, savings and investments means an even wider group of older people could face financial difficulties when their partner dies, whether these difficulties are short-lived or longer lasting," says researcher Anne Corden of the Social Policy Research Unit, University of York
When treating the diabetes patient, doctors discussed how a "one size fits all" approach to testing is not enough to reveal an individual"s risk for cardiovascular disease Saturday at the American Association of Clinical Endocrinologists (AACE) 18th Annual Meeting & Clinical Congress.
As President Obama prepares to sign a bill giving the Food and Drug Administration (FDA) oversight of the tobacco industry, a new study from Harvard School of Public Health (HSPH) researchers shows that tobacco manufacturers have continually changed the ingredients and the design of their cigarettes over time, even if those changes have exceeded acceptable product variance guidelines. The result, say the researchers, is that consumers who buy the same brand of product are not made aware of how that product has been altered and what effect those alterations might have on their levels of addiction or harm.
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKII alpha) is an enzyme that adds phosphates to a variety of protein substrates to modify their functions. CaMKII alpha is enriched in the hippocampus, the memory center of the brain, and is believed to be an essential mediator of activity-dependent synaptic plasticity and memory functions. However, the causative role of the enzymatic activity of CaMKII alpha in such processes has not been demonstrated yet, because this enzyme has multiple protein functions other than the kinase activity. A Japanese research group, led by Dr Yoko Yamagata of the National Institute for Physiological Sciences, Japan, has successfully generated a novel kinase-dead mutant mouse of the CaMKII alpha gene that completely and exclusively lacks its kinase activity. They examined hippocampal synaptic plasticity and behavioral learning of the mouse, and found a severe deficit in both processes. They reported their findings in the Journal of Neuroscience, published on June 10, 2009.
A PET scan uses radiation, or nuclear medicine imaging, to produce 3-dimensional, color images of the functional processes within the human body. PET stands for positron emission tomography. The machine detects pairs of gamma rays which are emitted indirectly by a tracer (positron-emitting radionuclide) which is placed in the body on a biologically active molecule. The images are reconstructed by computer analysis. Modern machines often use a CT X-ray scan which is performed on the patient at the same time in the same machine.
Patricia A. Furlong, Founding President and CEO of Parent Project Muscular Dystrophy (PPMD), the largest non-profit organization in the United States focused on finding a cure for Duchenne muscular dystrophy (Duchenne), announced that PPMD will be honoring United States Senator Johnny Isakson and the American Football Coaches Association (AFCA) with "Change It Champion" awards at the 2009 Connect Conference in Atlanta, Georgia on Saturday, June 27. Other award recipients include Darius Weems and Logan Smalley from the acclaimed documentary "Darius Goes West."
Exosome Diagnostics, Inc. ("ExosomeDX") and DxS Ltd. ("DxS") announced that they will collaborate on the development of blood-based companion diagnostics for key cancer gene mutations, such as KRAS, BRAF and EGFR. The collaboration will use DxS" industry leading Scorpions(R) real-time PCR Mutation Test Kits in conjunction with ExosomeDX"s xOS(TM) technology which harvests high-quality nucleic acids from blood exosomes.
A significant study was released today demonstrating the efficacy of Interactive Patient Care technology on improving outcomes in heart failure care.
New research sheds light on how cocaine regulates gene expression in a crucial reward region of the brain to elicit long-lasting changes in behavior. The study, published by Cell Press in the May 14th issue of the journal Neuron, provides exciting insight into the molecular pathways regulated by cocaine and may lead to new strategies for battling drug addiction.
Biopure Corporation (Nasdaq: BPUR) announced that the Food and Drug Administration has advised the U.S. Naval Medical Research Center (NMRC) by letter that it may not initiate a clinical trial of Biopure"s oxygen therapeutic Hemopure(R) [hemoglobin glutamer -- 250 (bovine)] under a proposed protocol submitted to the FDA in March 2009. As previously announced, the study, "Restore Effective Survival in Shock" (RESUS) was first proposed and submitted to the FDA in 2005. The proposed trial was placed on clinical hold at that time. It has been resubmitted repeatedly in response to FDA comments and to address comments made by the FDA Blood Products Advisory Committee at an open meeting held in December 2006. Each subsequent submission, including the most recent, was placed on clinical hold.
Loss of muscle strength, speed and dexterity is a common consequence of aging and a well-established risk factor for death, disability and dementia. Yet little is known about how and why motor decline occurs when it is not a symptom of disease.
Cancer the word resonates in people"s nightmares and strikes fear in the hearts of millions. Can there be a positive side amidst the panic, anxiety and hopeless feelings that often accompany the word? The answer is yes according to Dr. Patricia Mumby, associate professor Loyola University Chicago Stritch School of Medicine Psychiatry and Behavioral Neurosciences Department and director of Loyola Cardinal Bernadine Cancer Center Psychosocial Oncology Service.
Essentialis Inc, a clinical stage pharmaceutical company, announced that it met its primary endpoint of statistically significant triglyceride reduction in a 90-patient Phase 2b trial of DCCR in dyslipidemic patients. The study encompassed both patients with very high triglycerides and mixed dyslipidemia and included normal weight, overweight and obese patients presenting with or without hypertension.
Research at the University of Leicester is focussing on a major killer in UK hospitals. In England and Wales, the national health statistics in 2007 showed that there were 8,324 death certificates which named Clostridium difficile. This is a bacterium which causes severe diarrhoea in humans and animals as the underlying cause of death, a 28% increase from 2006.
A call for research on the emerging influenza pandemic is being launched by the NIHR as the World Health Organization (WHO) announces the move to pandemic phase 6. The research will provide evidence to influence ongoing health policy and practice.
David L. Shern, Ph.D., President and CEO of Mental Health America, will testify on Tuesday, June 23 before the Health Subcommittee of the Energy and Commerce Committee in a hearing to discuss a comprehensive health care reform bill unveiled last week by the Chairmen of the three lead health care reform committees in the House of Representatives: Energy and Commerce, Ways and Means, and Education and Labor.
"No one can figure out a politically acceptable way to pay for an overhaul of America"s health care system, and until someone does, the effort is stalled. Maybe indefinitely," McClatchy reports. Michael Tanner, a "health care analyst" at the Cato Institute, says "it"s quite feasible that the whole thing could crash and burn because of sticker shock." The Senate Finance Committee has postponed writing legislation until July. "Legislative committees plan hearings and bill-writing sessions next week, and will face two key cost-related obstacles: No one really knows any plan"s price tag, and few so far are willing to take the political risk of raising taxes to pay for it. Add to that growing public wariness: Polls show people are increasingly disturbed by record federal deficits. A Wall Street Journal/NBC News poll conducted June 12 to 15 found that 58 percent said that the president and Congress should focus most on keeping the deficit down, even if that means it will take longer for the economy to recover."
A Congressional committee recently turned its attention to rescission, a practice where insurers retroactively revoke plans to avoid paying high costs. NPR reports: "According to a new report by congressional investigators, an insurance company practice of retroactively canceling health insurance is fairly common, and it saves insurers a lot of money. A subcommittee of the House Energy and Commerce Committee recently held a hearing about the report"s findings in an effort to bring a halt to this practice. But at the hearing, insurance executives told lawmakers they have no plans to stop rescinding policies."
The National Minority Quality Forum (NMQF) today launched an online tool that maps the prevalence of HIV and AIDS by county, age, gender and ethnicity in all 50 states, Washington, D.C., Puerto Rico and the U.S. Virgin Islands, the San Francisco Chronicle reports. The HIV/AIDS Atlas is based on 2006 data collected from states and cross-checked with CDC data. The NMQF partnered with George Washington University"s School of Public Health and Health Services to collect and analyze the data. Gary Puckrein, chief executive officer of NMQF, said the new tool will help improve data collection and analysis, prevention initiatives, early diagnosis and routine testing efforts in areas most affected by HIV/AIDS (Colliver, San Francisco Chronicle, 6/21).
The National Organization for Women on Saturday during its annual conference elected Terry O"Neill as the group"s new president, the Indianapolis Star reports. O"Neill succeeds Kim Gandy, who has served two four-year terms as NOW president. The group has grown to include about 500,000 advocate members since its founding in 1966.During the conference, participants discussed a number of women"s rights issues, including same-sex marriage, equal pay and health insurance affordability. O"Neill raised the issue of "conscience" clauses, which allow health care workers to refuse to provide information or services on moral or religious grounds. O"Neill said, "Conscience clauses, where pharmacists refuse birth control sales because it"s against their conscience, must go. Guess what? Women have a constitutional right to birth control," adding, "There is no constitutional right to be a pharmacist" (Jacobs, Indianapolis Star, 6/21).O"Neill served as NOW"s vice president for membership from 2001 to 2005. She most recently served as chief of staff for a county council member in Montgomery County, Md. O"Neill in a prepared statement said that she is "honored and eager" to lead NOW (AP/Google.com, 6/21).
In a recent phase II clinical trial, the drug alemtuzumab (Campath-1H) was found to be a highly effective treatment for individuals with early relapsing-remitting multiple sclerosis. However, a substantial proportion of the patients treated (30%) went on to develop another autoimmune disease, mostly thyroid autoimmunity. Now, Joanne Jones and colleagues, at the University of Cambridge, United Kingdom, have determined that individuals with higher levels of the soluble factor IL-21 in their blood prior to alemtuzumab treatment were those that went on to develop an autoimmune disease. Further analysis identified a mechanism by which IL-21 contributes to the development of autoimmunity and determined that in some patients the higher levels of IL-21 were genetically predetermined. The authors therefore suggest that measuring levels of IL-21 in the blood of individuals with early relapsing-remitting multiple sclerosis might identify those that would be at greatest risk of developing autoimmunity if treated with alemtuzumab. Terri Laufer and Gregory Wu, at the University of Pennsylvania, Philadelphia, further discuss the importance of this in an accompanying commentary, noting that determining one reason why some patients succumb to autoimmune disease after alemtuzumab treatment, while others do not, is likely to increase enthusiasm for this new therapeutic.
The natriuretic peptide (NP) receptor type B (NPR-B) gene was expressed in gastric smooth muscles of normal and diabetic rats and the expression was increased in diabetic rats. These results suggest that natriuretic peptide-dependent pGC-cGMP signal is up-regulated and it may contribute to diabetic gastroparesis in STZ-induced diabetic rat.
A study published in the July issue of Anesthesiology offers perhaps the first estimation of how genomic copy number variation (CNV) can influence anesthetic sensitivity and the magnitude of this influence.
Zannos Grekos, MD, Associate Clinical Professor at Nova Southeastern University, has announced six month follow-up results for a patient treated with adult stem cells in a clinical study of idiopathic dilated cardiomyopathy. The clinical study is a collaborative effort among physicians at Regenocyte Therapeutic, an American stem cell therapy clinic; researchers and scientists from Theravitae, a biotechnology company from Israel; and physicians from the American Institute for Regenerative Medicine, Dominican Republic.
Today, President Obama took historic action to save lives, reduce health care costs, and help reduce suffering from heart and lung diseases, cancer, and other tobacco-related illnesses. These illnesses kill hundreds of thousands of Americans every year, and the new law gives us the tools to effectively address this major public health issue. This is a key step forward and an important part of health reform.
Ceragenix Pharmaceuticals, Inc.("Ceragenix") (OTCBB:CGXP), a medical device company focused on infectious disease and dermatology, announced that researchers at National Jewish Health, led by Dr. Donald Y. Leung and Dr. Michael Howell, in collaboration with Dr. Paul B. Savage of Brigham Young University, have demonstrated in a series of in vitro experiments and preclinical animal testing that an investigational drug compound known as CSA-13 shows promise as a potential therapy to treat viral infections from the vaccinia virus. The research appears ahead of print in an advanced online publication of the Journal of Investigate Dermatology, the official journal of the Society for Investigative Dermatology. This work was funded by the National Institute of Allergy and Infectious Diseases Atopic Dermatitis Vaccinia Network.
Select Rite Aid stores nationwide will host Diabetes Solutions Days on June 23 and 25 offering patients living with diabetes valuable health screenings and self-management solutions. Caregivers and patients alike can benefit from this free chance to get professional advice on the symptoms and treatments for diabetes as well as watching hands-on demonstrations.
In a paper in Nature Geoscience, a team from the National Oceanography Centre, Southampton (NOCS), along with colleagues from TÃøbingen (Germany) and Bristol presents a novel continuous reconstruction of sea level fluctuations over the last 520 thousand years. Comparison of this record with data on global climate and carbon dioxide (CO2) levels from Antarctic ice cores suggests that even stabilisation at today"s CO2 levels may commit us to sea-level rise over the next couple of millennia, to a level much higher than long-term projections from the Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC).
Physiological and biochemical changes that occur during fasting in Ramadan are not a risk factor for stroke and do not affect the short-term survival of patients. This is the result of a study by a team of researchers from the Isfahan University of Medical Sicences (Iran). The data are being presented at the annual meeting of the European Neurological Society in Milan (Italy).
Telecoms, healthcare and display technology will be the major beneficiaries of a new generation of semiconductor lasers developed in a massive European research effort. Better cancer treatment, wider bandwidth and smaller, better displays could be on their way.
Total knee replacement (arthroplasty) appears to be a cost-effective procedure for older adults with advanced osteoarthritis, according to a report in the June 22 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. The procedure appears to be cost-effective across all patient risk groups, and appeared more costly and less effective in low-volume centers than in high-volume centers.
A good partner relationship can act as a buffer for those exposed to work-related stress.
New research which suggests a direct link between smoking and brain damage will be published in the July issue of the Journal of Neurochemistry. Researchers, led by Debapriya Ghosh and Dr Anirban Basu from the Indian National Brain Research Center (NBRC), have found that a compound in tobacco provokes white blood cells in the central nervous system to attack healthy cells, leading to severe neurological damage.
Health workers fail to understand the importance of sex for Tanzanian children
A landmark study has successfully demonstrated a 29 percent reduction in heart failure or death in patients with heart disease who received an implanted cardiac resynchronization therapy device with defibrillator (CRT-D) versus patients who received only an implanted cardiac defibrillator (ICD-only).
"Addiction is on the upswing, fueled by pressures from our economic downturn," says Howard Meitiner, President and CEO of Phoenix House, the nation"s largest non-profit alcohol and drug abuse treatment and prevention facility. "Eighty-eight percent of the population feels that drug abuse is at either serious or crisis levels today, reflecting the devastating impact that addiction is having on individuals, families, and communities."
OncoGenex Pharmaceuticals, Inc. (NASDAQ: OGXI) announced the release of two abstracts to be presented during oral presentations at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting. Abstracts are now available to the public online on the OncoGenex Web site at http://www.oncogenex.com in addition to the ASCO Web site, http://www.abstract.asco.org.
While suffering a major stroke at her home near Mena, Iva Sikes assumed the worst, not knowing that a University of Arkansas for Medical Sciences (UAMS)-led telemedicine program would provide her a complete recovery.
More than 500 scientific abstracts to be presented across 20 types of
The White House launches a media blitz this week to coincide with the shrinking timeline for getting a health reform package passed in the Senate, Roll Call reports.
Tonia Odom, a 35-year-old patient with rheumatoid arthritis, a sick father and a young son, each of whom has multiple health problems, has found some relief to the problems of managing her families" array of illnesses in at a Duke University clinic that"s a model of the "medical home" approach to medicine, the New York Times reports. "As President Obama and Congress try to create a national system that provides better care for more people at lower cost, you are likely to hear a lot more about this idea. The term, coined by the American Academy of Pediatrics in 1967, is admittedly confusing. It does not mean a return to house calls. Nor need it apply only to people with complex health problems like those of the Odom family."
"As sentiment and the stock market increasingly look bearish, look for the recent outperformance in health care to continue," The Wall Street Journal reports. Health-care firms were "hardly a leader" during the "initial run of stocks following the March lows," but they also "fared much better during the market"s plummet. Last week, "health care was the one exception to a sliding market." Katie Stockton, chief market technician for MKM Partners, "says it is likely most of the health-care sector will outperform and not just large pharmaceutical companies" (Rogow, 6/23).
The H1N1 (swine flu) virus has now infected more than 52,000 people, leaving 231 dead, the WHO said Monday, AFP/Washington Post reports. "Swine flu has now been reported in 100 countries and territories, and figures yet to be incorporated into the U.N. health agency"s official figures indicate an even higher toll," AFP/Washington Post writes, adding, "The WHO said, however, that its figures could not be considered reliable because some countries were no longer keeping total figures while other poor countries did not have the means to reliably detect cases." Since Friday, the number of cases has grown by more than 7,873 cases and 51 deaths, "highlighting the steady spread of the virus," the newspaper writes (AFP/Washington Post, 6/23).
Refinements of the definitions, classifications, and interpretations of fetal heart rate (FHR) monitoring methods were issued today in new guidelines released by The American College of Obstetricians and Gynecologists (ACOG). The objective of the guidelines is to reduce the inconsistent use of common terminology and the wide variability that sometimes occurs in FHR interpretations. ACOG"s Practice Bulletin, published in the July 2009 issue of Obstetrics & Gynecology, supports the recommendations of the Eunice Kennedy Shriver National Institute of Child and Health Development workshop* on electronic fetal monitoring (EFM) held in April 2008.
Wiley-Blackwell, the scientific, technical, medical and scholarly publishing business of John Wiley & Sons, Inc., has launched an online reference website offering free access to top quality research articles and publications relating to Influenza A H1N1. The complimentary content includes articles from the Cochrane Library, The Hospitalist, and From Influenza and Other Respiratory Viruses, among other books and journals.
University of Minnesota Medical School researchers have discovered an important new insight into how a commonly prescribed drug may work to treat those infected by a parasitic flatworm.
Meckel"s diverticulum (MD) is the most frequent congenital abnormality of the small bowel and it is often difficult to diagnose. It is usually asymptomatic but approximately 4% are symptomatic with complications such as bleeding, intestinal obstruction, and inflammation. Daniela Codrich et al presents a case of Meckel"s diverticulum masked by a long period of intermittent recurrent subocclusive episodes. Their findings were published on June 14, 2009 in the World Journal of Gastroenterology.
The NHS Institute for Innovation and Improvement has sent every NHS trust in England a new kit designed to help radiology departments review and assess their booking processes for the benefit of both patients and staff.
Multiple sclerosis, diabetic neuropathy, and other conditions caused by a loss of myelin insulation around nerves can be debilitating and even deadly, but adequate treatments do not yet exist. That"s in large part because of deficiencies in model research systems. In an upcoming issue of the journal Biomaterials, a UCF team addresses this problem with a report on the first lab-grown motor nerves that are insulated and organized the same way they are in the body. The group"s model system, along with further advances now within reach, could dramatically improve understanding of the causes of myelin-related conditions, and enable discovery and testing of new drug therapies.
According to the American Diabetes Association, nearly 24 million people have diabetes. Of that number, unfortunately, 5.7 million people are unaware that they have the disease. Diabetes can affect multiple parts of the body, including the kidneys, nerves, heart and even the mouth.
Atrial fibrillation (AF) is the most common arrhythmia, affecting an estimated 7 million people worldwide, including 4.5 million in the European Union1,2. Data presented today as a Hot Line session at the EUROPACE 2009 congress on the XPECT clinical trial, sponsored by Medtronic, Inc. (NYSE: MDT), shows that the Medtronic Reveal® XT Insertable Cardiac Monitor (ICM) reliably identifies patients with AF (sensitivity of 96.1 percent) and correctly confirms the absence of AF in patients (negative predictive value of 97.4 percent).
Resolvyx Pharmaceuticals, Inc., the leading resolvin therapeutics company, today announced that it has initiated the first human clinical trial evaluating an oral resolvin therapeutic, RX-10001, in a Phase I clinical trial in healthy volunteers. RX-10001 is a synthetic form of RvE1, a naturally occurring resolvin, which in animal studies has been shown to activate the body"s own off-switch mechanisms for inflammation and to promote healing for normal tissue function. In preclinical testing, RX-10001 and analogs have shown high potency across a range of inflammatory disease models, including asthma, colitis, rheumatoid arthritis, and atherosclerosis.
The Northern California Melanoma Center (NCMC)"s research showed patients who received GM-CSF (Sargramostim, trade name Leukine) may experience prolonged survival. The study appears in next month"s Journal of Immunotherapy (July/August issue) and will appear online today.
Robert Wood Johnson University Hospital and UMDNJ-Robert Wood Johnson Medical School jointly announce the successful implant of the AbioCor® Total Replacement Heart, the world"s first completely self-contained, fully implantable artificial heart, as well as the first internal artificial organ. The surgery was led by Mark Anderson, MD, associate professor of surgery at UMDNJ-Robert Wood Johnson Medical School and chief of the section of cardiac surgery at both the medical school and Robert Wood Johnson University Hospital, and assisted by Juan Plate, MD, assistant professor of surgery at UMDNJ-Robert Wood Johnson Medical School and an attending surgeon at Robert Wood Johnson University Hospital. Robert Wood Johnson University Hospital is one of only three centers nationwide approved to perform the surgery and the only one in the New York and Philadelphia areas. Dr. Anderson is one of a handful of physicians nationwide trained to perform this procedure. This is the first time the AbioCor has been implanted in a patient since the completion of clinical trials and approval by the Food and Drug Administration.
The emerging field of synthetic biology draws on a variety of technologies, including genetic engineering and nanotechnology, to engineer biological systems to perform novel tasks. As the science and its applications develop, instead of creating a "new kind" of ethics for each new techno-scientific arena, a comprehensive approach is needed to address ethical and social issues of emerging technologies as a whole, according to a report by Erik Parens, Josephine Johnston, and Jacob Moses of The Hastings Center. Synthetic biology promises significant advances in areas such as biofuels, specialty chemicals, agriculture, and medicine but also poses potential risks.
Latest Erbitux® (cetuximab) data presented today at the World Congress on Gastrointestinal Cancer (WCGIC) reinforce the value of the targeted therapy in the treatment of metastatic colorectal cancer (mCRC) patients with KRAS wild-type (wt) tumors. Results from the CRYSTALa and CELIMb trials have provided further evidence that KRAS mutation status is the current accepted standard predictive biomarker for Erbitux efficacy in patients with mCRC. In addition, new data have shown that the rash associated with Erbitux therapy can be effectively treated with a cream containing vitamin K.
"As President Obama"s effort to overhaul the health care system seems to hit one roadblock after another in Congress, he is counting on Senator Max Baucus [D-Mont.], a political shape-shifter and crafty deal maker who is not fully trusted by either party, to help him clinch his top domestic priority," the New York Times reports in a profile of the Senate Finance Committee leader. Sen. Chris Dodd, D-Conn., has been unable to garner GOP support. Obama"s preferred health leader, Tom Daschle, dropped out of the Obama team because of tax problems and highly partisan House Democrats have failed to work with Republicans, leaving the task of ushering a bill through the legislative process largely to Baucus.
Namibia"s recently released second MDG Report 2008 finds that the country is making progress toward achieving some of the U.N. Millennium Development Goal (MDG) targets. However, the Prime Minister says the global economic situation could reverse progress and notes that the country is behind on some health-related targets, New Era reports.
The Rheumatology Futures Project and the Department of Health have launched a new 18-week commissioning pathway for inflammatory arthritis (IA).
Effective drugs for treating a chemotherapy-resistant form of lymphoma might already be on the market according to a study that has pieced together a chemical pathway involved in the disease.
A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States.
Despite recent declines in cigarette use in the U.S., nicotine dependence has remained steady among adults and has actually increased among some groups. The finding by researchers at Columbia University Mailman School of Public Health suggests that public health initiatives have been far more successful in preventing Americans from taking up smoking than in persuading hard-core smokers to stop. The study is available online in the American Journal of Public Health and will be published in the August 2009 issue.
The NPA has launched an exciting new service enabling members to offer seasonal flu vaccinations to customers under a private Patient Group Direction (PGD) that the NPA is facilitating for its members, in line with our objective to provide additional business opportunities. Currently regulators require registration with the Health Care Commission and the involvement of a medical agency before a private PGD service can be set up. Members can now set up new services under private PGD without having to undertake this bureaucratic burden themselves.
Apthera, Inc. announced that it reached an agreement with the U.S. Food and Drug Administration (FDA) under a Special Protocol Assessment (SPA) for its planned Phase III clinical trial of the Company"s lead drug, NeuVax. The SPA is a written agreement between the trial"s sponsor and the FDA regarding the design, endpoints, and planned statistical analysis of the Phase III trial to be used in support of a Biologics License Application (BLA).
The social class, the gender and the ethnic group are three essential dimensions, not only in the social differentiation, but also in the affective sexual education of the adolescents, where it is necessary to take part in order to promote sexual and gender equity and prevent gender violence. This is one of the main conclusions of the investigation Affective sexual policy: a sociological approach to affective sexual education", carried out by the researcher of the department of Sociology of the University of Granada Mar Venegas Medina and supervised by professor Francisco Fernández Palomares.
Parts of the right hemisphere of the brains of people with dyslexia have been shown to differ from those of normal readers. Researchers writing in the open access journal BMC Neuroscience used magnetic resonance imaging (MRI) to compare the two groups, and were able to associate the neurological differences found with different language difficulties within the dyslexic group.
Global warming will likely mean more unpredictable weather, scientists say, and a new study by researchers at the University of Georgia pins down, possibly for the first time, how drought conditions in an area"s fall and winter may effect tornado activity the following spring.
Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular behavior.
- 0 confirmed cases in Wales.
Frankenman International Ltd, the manufacturer and supplier of surgical instruments, announced that its entire CHEX™ range of surgical staplers had been granted FDA approval. This development complements the CE and ISO accreditation it has already acquired. FDA approval endorses Frankenman"s commitment to total quality in surgical stapling and wound closure devices, and further validates its position as a trusted alternative supplier in these markets.
The European Medicines Agency"s (EMEA) Committee for Medicinal Products
Insmed Inc. (Nasdaq: INSM), a biopharmaceutical company, announced results from its exploratory U.S. Phase II clinical trial evaluating IPLEX(TM) (mecasermin rinfabate) in patients with myotonic muscular dystrophy ("MMD"). The randomized, double-blind, placebo-controlled Phase II trial conducted in 13 centers across the U.S. enrolled 69 patients with MMD, for a six-month period. As this was an exploratory trial, a primary endpoint was not pre-defined. The trial explored measures of endurance, using the six-minute walk test, muscle function and strength, cognitive function, gastrointestinal function, pain, quality of life, insulin sensitivity, lipid metabolism, and safety and tolerability of IPLEX(TM).
More pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from The Children"s Hospital of Philadelphia, the University of Pennsylvania School of Medicine and several collaborating institutions. This study identified 27 different genetic regions where rare copy number variations missing or extra copies of DNA segments were found in the genes of children with autism spectrum disorders (ASDs), but not in the healthy controls. The complex combination of multiple genetic duplications and deletions is thought to interfere with gene function, which can disrupt the production of proteins necessary for normal neurological development.
Kidney injury that can arise after undergoing certain medical imaging procedures increases a patient"s risk of having a stroke or heart attack over the next year or two, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings indicate that seemingly minor and reversible kidney damage from these common clinical procedures is a serious health threat.
The National Center for Catastrophic Sports Injury Research based at the University of North Carolina at Chapel Hill has released its 26th annual all sports report.
Some patients with large tumors on their larynx can preserve their speech by opting for chemotherapy and radiation over surgery to remove the voice box.