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New Model Suggests Role Of Low Vitamin D In Cancer Development
In studying the preventive effects of vitamin D, researchers at the Moores Cancer Center at the University of California, San Diego, have proposed a new model of cancer development that hinges on a loss of cancer cells" ability to stick together. The model, dubbed DINOMIT, differs substantially from the current model of cancer development, which suggests genetic mutations as the earliest driving forces behind cancer.

Researchers Suggest That Oxidative Stress Is Strongly Evident In The In-Utero Environment Of The Fetus With Down Syndrome
A paper published in the Proceedings of the National Academy of Sciences by Tufts Medical Center and Tufts University researchers reports that amniotic fluid surrounding Down syndrome fetuses shows oxidative stress, a condition that could harm fetal cells and play a role in affected individuals. The results demonstrate secondary adverse consequences of Down syndrome and suggest potential prenatal therapies.
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Bionovo Presents Positive Results From Phase 1B Trial Of Bezielle For Metastatic Breast Cancer
Bionovo, Inc. (Nasdaq: BNVI) announced positive results from the Phase 1B clinical trial of Bezielle (formerly BZL101), their lead drug candidate for advanced breast cancer. In the trial, Bezielle showed an excellent safety and tolerability profile, and also showed promising indications of efficacy in a difficult-to-treat population.
Endocrinology

RCOG/RCM Statement - Advice On Swine Flu And Pregnancy

Update 20 July 2009: Statement from the Royal College of Obstetricians and Gynaecologists (RCOG) and the Royal College of Midwives (RCM) about the recent news about advice for pregnant women in Australia and New Zealand. Recent news reports have suggested that pregnant women in Australia and New Zealand have been advised to wear masks in public and stay at home if possible to reduce the risk of swine flu infection. The latest guidance issued by the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) recommends that "pregnant women should avoid unnecessary exposure to crowded areas but complete isolation at home would be regarded as extreme for most women." Experience with the current disease pattern shows that in most cases, swine flu tends to be a mild respiratory disease. A few cases of severe illnesses among pregnant women and infants have been reported in the UK and other countries. These have mostly affected women with pre-existing health problems. UK Advice for pregnant women Current guidance in the UK for pregnant and breastfeeding women remains unchanged. - Pregnant women are advised to practice good hand hygiene by washing hands frequently with soap and water. - Tissues should be used to cover the mouth and nose when sneezing and coughing - Used tissues should be disposed of promptly. - Pregnant women are advised to avoid crowded places when possible. - Women who experience any symptoms of swine flu should contact the National Flu Service (Call the Swine Flu Information Line on 0800 1 513 513). Women with symptoms of the influenza who have been advised by the National Flu Service to take antiviral medication should do so. Once the antiviral treatment is authorized, women should arrange for a Flu Friend to collect the antiviral on their behalf. They should follow the advice to stay at home until they become symptom free. There is currently no evidence to suggest that the use of antiviral medication might cause harm to the baby. During pregnancy, it is also important to treat fever (high temperature). This can be controlled by taking paracetamol which is known to be safe in pregnancy. The Royal College of Obstetricians and Gynaecologists (RCOG) and the Royal College of Midwives (RCM) will continue to work with the Department of Health to monitor disease trends, ensure appropriate planning for maternity services, and provide regular updates and recommendations. Further information The Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG) statement on H1N1 Influenza and Pregnancy (17 July 2009) is available RANZCOG website The recent news article in the Sydney Morning Herald is available here: Sydney Morning Herald website RCOG advice for pregnant women and updates on swine flu are available here: RCOG website Royal College of Obstetricians and Gynaecologists


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