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FDA Approves VYVANSE CII Label Change To Include Supplementary Clinical Data Supporting Efficacy At 13 Hours Postdose In Children Age 6-12 With ADHD
Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced that the US Food and Drug Administration (FDA) has approved a change to the prescribing information for its once-daily Attention Deficit Hyperactivity Disorder (ADHD) treatment VYVANSE® (lisdexamfetamine dimesylate) CII, to include supplemental data that demonstrated significant ADHD symptom control in children aged 6 to 12 from the first time point measured (1.5 hours) through 13 hours postdose. VYVANSE is now the first and only oral ADHD stimulant treatment to have 13-hour postdose efficacy data for pediatric patients included in its product labeling.

Biological Link Established Between Tumors And Depression
In a study that could help explain the connections between depression and cancer, researchers at the University of Chicago have used an animal model to find, for the first time, a biological link between tumors and negative mood changes.
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This Time Around, Debate Much Different
Insurance companies, "the industry that gets credit for helping to kill the Clinton administration"s health care overhaul 15 years ago," are now "striking a conciliatory tone as it faces the most serious attempt to overhaul the system since that effort collapsed," CQ Politics reports. With low favorability ratings and Democrats in control of the federal government, "insurers know they aren"t in a good bargaining position" this time around. They have already offered concessions, including providing "insurance in the individual markets to everyone, without regard to who is sick," and not "charging people who are ill higher rates and cut health care costs." But they"ve also been ""careful to structure their offers in such a way that appears significant but does not overpromise." An individual mandate for all Americans and an end to health screening for applicants could offer "a win-win outcome, one that will benefit not just patients but potentially the profits of the industry as well." But "perhaps the biggest motivation for insurers to deal now is that they fear what might happen if they don"t" - the "creation of a government-run plan that would be more attractive to the public and siphon off customers" (Adams, 6/1).
Endocrinology

Popular Television Shows Inaccurately Portray Violent Crime According To Mayo Clinic Researchers

Researchers at Mayo Clinic compared two popular television shows, CSI and CSI: Miami, to actual U.S. homicide data, and discovered clear differences between media portrayals of violent deaths versus actual murders. This study complements previous research regarding media influences on public health perception. Mayo Clinic researchers presented their findings at the American Psychiatric Association annual meeting in San Francisco. Previous studies have indicated television influences individual health behaviors and public health perceptions. Timothy Lineberry, M.D., a psychiatrist at Mayo Clinic, says "We make a lot of our decisions as a society based on information that we have, and television has been used to provide public health messages." Researchers chose to compare the crimes on CSI and CSI: Miami to real homicides because of the shows" combined audiences of more than 43 million viewers annually. They sought to determine how representative the portrayal of violent death crimes on the two series compared with data from the Centers for Disease Control (CDC) National Violent Death Reporting System. When researchers compared the shows to the CDC data, they discovered the strongest misrepresentations were related to alcohol use, relationships, and race among perpetrators and victims. Previous studies of actual statistics have shown that both perpetrator and victim were often under the influence of alcohol and/or drugs when the crime occurred, differing from what the shows portrayed. Also, CSI and CSI: Miami were more likely to have described the victim and the attacker as Caucasian, which is misrepresentative. Finally, according to the CDC data, homicide victims typically knew their assailant; however, the television series were more likely to have portrayed the perpetrator as a stranger. All of these findings were significantly different when compared to the data. Dr. Lineberry says, "If we believe that there is a lack of association with alcohol, that strangers are more likely to attack, and that homicide doesn"t represent particular groups of people, it"s difficult to create public health interventions that the general public supports." Other authors contributing to this study included Christopher Janish and Melanie Buskirk, both from Mayo Medical School. John Murphy Mayo Clinic


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