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Preemies Born In Poverty Four Times Less Likely To Be Ready For School
Advances in neonatal care enable two-thirds of premature babies born with respiratory problems to be ready for school at an appropriate age, but those living in poverty are far less likely to be ready on time than their better-off peers, researchers from the University of Chicago Medical Center report in the July issue of the journal Pediatrics.

Important Therapeutic Target For Breast Cancer: Newly Appreciated Membrane Estrogen Receptor
New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. This new study by Edward Filardo, MD, and his research team further supports earlier published work by the group that linked the transmembrane receptor, GPR30/GPER-1, to specific estrogen binding, rapid estrogen signaling and breast cancer metastasis. "What is exciting about this new work," says Filardo, "is that it provides some insight into the influence of GPR30 at the cellular level. It shows that estrogen action through GPR30 allows for breast tumor cell survival, and not breast tumor cell proliferation." Prior studies by Filardo"s group showed that estrogen acts through GPR30 to promote the rapid release of preformed growth factors that are tethered to the surface of breast cancer cells. Their latest study was conducted in an effort to better understand the mechanism by which GPR30 triggered the release of epidermal growth factor (EGF) polypeptides from the surface of breast cancer cells.
News of the day
Does Synthetic Biology Need Synthesized Ethics?
The emerging field of synthetic biology draws on a variety of technologies, including genetic engineering and nanotechnology, to engineer biological systems to perform novel tasks. As the science and its applications develop, instead of creating a "new kind" of ethics for each new techno-scientific arena, a comprehensive approach is needed to address ethical and social issues of emerging technologies as a whole, according to a report by Erik Parens, Josephine Johnston, and Jacob Moses of The Hastings Center. Synthetic biology promises significant advances in areas such as biofuels, specialty chemicals, agriculture, and medicine but also poses potential risks.
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New Risk Factors For Teen Self Harm

A lack of emotional intelligence leads to poor coping strategies and seriously increases the likelihood of self-harm in teenagers, claims a study published yesterday, in the British Journal of Clinical Psychology. The study, carried out by Moira Mikolajczak from the Universite Catholique de Louvain, Belgium, K. V. Petrides from the London Psychometric Laboratory at University College London and Jane Hurry from the Institute of Education examined the levels of self harm, emotional intelligence and coping strategies of 490 British secondary school pupils. Dr Petrides said: "People who turn to self harm claim to do so to regulate their emotions, which indicates that they cannot manage their feelings in a healthy way. We wanted to better understand the underlying psychological issues that lead adolescents to harm themselves." Of the 490 students who took part, 132 (27 per cent) reported having deliberately self harmed, either hitting or cutting themselves or taking an overdose of recreational drugs. 65 per cent of self harmers were found to have mild to severe symptoms of depression. "We found that teenagers who self harmed had both significantly lower scores on a measure of emotional intelligence and were more likely to use maladaptive coping strategies such as self criticism or self blame. This suggests that self harm is a desperate attempt to reduce the negative feelings that are worsened by their poor and ineffective emotional coping strategies." "However efficient self harm may be at reducing negative emotions in the short term, this is at the cost of serious physical injury and longer term psychological problems. These findings will help us develop coaching programmes for the treatment of self harm patients that focus on developing both better methods of coping and boosting emotional intelligence." British Psychological Society


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