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Mersana Reports Preliminary Phase 1 Results Of XMT-1001 In Patients With Advanced Solid Tumors
Mersana Therapeutics presented preliminary results of a Phase 1 clinical trial for its lead development candidate, XMT-1001, in a poster session at the 2009 Annual Meeting of the American Society of Clinical Oncology (ASCO) in Orlando. XMT-1001 is a broad-spectrum cytotoxic, based on camptothecin (CPT), conjugated to Mersana"s biodegradable polymer platform, Fleximer(R).

Obama Says Health Reform Must Be Done This Year
The opportunity to enact health care reform legislation could be missed unless Congress passes it this year, President Obama on Thursday said to thousands of supporters in a phone call made from Air Force One, the AP/USA Today reports. In a call to members of his political organization, Organizing for America, Obama said, "If we don"t get it done this year, we"re not going to get it done," adding, "I think the status quo is unacceptable and that we"ve got to get it done this year." Obama also said that any action on overhaul legislation could be delayed unless volunteers pressure lawmakers to support the administration"s goals for health care reform (AP/USA Today, 5/28). Obama said, "Some of you are in states and districts where politicians are resistant to bringing about change, so we need you to get involved" (Zeleny, "The Caucus," New York Times, 5/28). Obama told volunteers that it was time to "remobilize" after their successful campaign to get him elected, adding that "we have gotten a lot of things done during our first four months. But health care, that"s a big push" (AP/USA Today, 5/28).David Plouffe, Obama"s presidential campaign manager and head of Organizing for America, during the call said, "If the country stands with the president and if the country is demanding health care reform, [then] we"ll get it done," adding, "Washington will not have any option but to follow us." He added, "You need to take ownership of this" ("The Caucus," New York Times, 5/28). Organizing for America Campaign
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Tragic Death Highlights Perils Of Binge Drinking, UK
Commenting on the tragic death of 22-year-old Gary Reinbach, who died as a result of binge drinking since the age of 13, Dr Peter Carter, Chief Executive of the Royal College of Nursing (RCN), said:
Endocrinology

Mindblind Eyes: An Absence Of Spontaneous Theory Of Mind In Asperger Syndrome

Highly intelligent adults with Asperger Syndrome still have difficulties in day-to-day social interaction. These difficulties may be explained by "mindblindness", the idea that they are unable to predict what other people will do by thinking about their mental states, that is, their knowledge and beliefs. If this is true then why do people with Asperger syndrome pass all the standard tests of mental state attribution? Is the theory wrong or are the tests insensitive? This study reports evidence from eye movements, that adults with Asperger Syndrome do not spontaneously anticipate another person"s behaviour on the basis of that person"s mental state. This is in stark contrast with typical adults, and even young toddlers. So the mindblindness theory also holds for highly intelligent people with Asperger syndrome. At the same time we acknowledge their successful compensatory learning. This suffices for slow and deliberate thinking about other people"s thoughts, but is not the same as the spontaneous and automatic ability to attribute inner thoughts, and it may be the lack of this spontaneous ability that is at the heart of the everyday social impairments still evident in highly intelligent adults with Asperger Syndrome. Birkbeck College


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