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Study Offers First Look At Effects Of Genetic Copy Number Variation On Volatile Anesthetics
A study published in the July issue of Anesthesiology offers perhaps the first estimation of how genomic copy number variation (CNV) can influence anesthetic sensitivity and the magnitude of this influence.

Structures From Immune System's Oldest Branch Shed Light On A Range Of Diseases
How molecules of the oldest branch of the human immune system have interconnected has remained a mystery. Now, two new structures, both involving a central component of an enzyme important to the complement system of the immune response, reveal how this system fights invading microbes while avoiding problems of the body attacking itself.
News of the day
More Gene Mutations Linked To Autism Risk
More pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from The Children"s Hospital of Philadelphia, the University of Pennsylvania School of Medicine and several collaborating institutions. This study identified 27 different genetic regions where rare copy number variations missing or extra copies of DNA segments were found in the genes of children with autism spectrum disorders (ASDs), but not in the healthy controls. The complex combination of multiple genetic duplications and deletions is thought to interfere with gene function, which can disrupt the production of proteins necessary for normal neurological development.
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Columnists Discuss HIV Statistics, National Testing Day

"It"s getting harder to convince people of the urgency, that knowing your HIV status is better than not knowing, that this is still a serious problem," columnist Wendi Thomas writes in the Memphis Commercial Appeal. She writes that some people "assume being HIV positive is no big deal" because former National Basketball Association player Earvin "Magic" Johnson has lived with HIV since 1991 and appears to be healthy. "But if you are HIV positive and delay finding out, the virus could progress" to a point where it becomes "much more difficult to treat," Thomas adds (Thomas, Memphis Commercial Appeal, 6/25). Philadelphia Inquirer columnist George Curry today discussed HIV statistics and findings from a recent Kaiser Family Foundation survey that looked at U.S. residents" views on HIV/AIDS. He said, "It"s time to refocus our attention on HIV and AIDS. And a good way to do that is by getting tested tomorrow" on National HIV Testing Day (Curry, Philadelphia Inquirer, 6/26). This information was reprinted from dailyreports.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily U.S. HIV/AIDS Report, search the archives and sign up for email delivery at dailyreports.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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